Requirement for NF-kappa B in osteoclast and B-cell development
نویسندگان
چکیده
منابع مشابه
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation.
Ligation of antigen receptors (TCR, BCR) on T and B lymphocytes leads to the activation of new transcriptional programs and cell cycle progression. Antigen receptor-mediated activation of NF-kappa B, required for proliferation of B and T cells, is disrupted in T cells lacking PKC theta and in B and T cells lacking Bcl10, a caspase recruitment domain (CARD)-containing adaptor protein. CARMA1 (al...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 1997
ISSN: 0890-9369
DOI: 10.1101/gad.11.24.3482